Bibliografische Daten
ISBN/EAN: 9781461423997
Sprache: Englisch
Umfang: xii, 328 S., 3 s/w Illustr., 34 farbige Illustr.,
Einband: gebundenes Buch
Beschreibung
InhaltsangabePreface.- The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies.- Molecular Biology of Clear Cell Renal Carcinoma.- HIF Biology in RCC: Implications for Signaling, Disease Progression, and Treatment.- Tissue Biomarkers in Renal Cell Carcinoma: Intermediate Endpoints in the Selection of Targeted Agents for RCC.- Molecular Characterization of Renal Cell Carcinoma.- Targeting The Vegf Pathway In Renal Cell Carcinoma.- Angiopoetins and Other Non-VEGF Antiangiogenic Targets In Advanced Renal Cell Carcinoma.- Towards Personalized Cancer Medicine.- Epigenetic Targeting and Histone Deacetylase Inhibition in RCC.- C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma.- Characterizing and Modulating the Tumor Micro-Environment in Renal Cell Carcinoma: Potential Therapeutic Strategies.- Carbonic Anhydrase IX: Its role as a biomarker, diagnostic, and therapeutic target in Renal Cell Carcinoma.- Presurgical Therapy for Renal Cell Carcinoma and Implications for Window of Opportunity Trials.- Mechanisms of Resistance to VEGF Directed Therapy and Implications for Future Trial Design.- Vaccine Based Immunotherapy and Targeting the Tumor Microenvironment in Renal Cell Carcinoma.- Index.